Description

3-(4-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile intermediate with a protected amine group for selective functionalization. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its piperazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected amine chemistry.
• Material Science Research: Investigated as a monomer or functional additive in the synthesis of advanced polymers and specialty materials.

Basic Information

Item	Details
Product Name	3-(4-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886768-17-8
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 3-(4-methoxyphenyl)piperazine-1-carboxylate; 1-Boc-3-(4-methoxyphenyl)piperazine; 3-(4-Methoxyphenyl)-1-(tert-butoxycarbonyl)piperazine; 1-N-Boc-3-(4-methoxyphenyl)piperazine; 3-(p-Methoxyphenyl)-1-Boc-piperazine; 886768-17-8; 3-(4-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 3-(4-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.