Description

2-(3-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and psychiatric drug candidates.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the optimization and pilot-scale production of target molecules.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides that require complex heterocyclic structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional Research: Used in university and institutional laboratories for fundamental organic chemistry and drug discovery research.

Basic Information

Product Name	2-(3-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886768-13-4
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 2-(3-methoxyphenyl)piperazine-1-carboxylate; 1-Boc-2-(3-methoxyphenyl)piperazine; 2-(3-Methoxyphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-(3-methoxyphenyl)piperazine; 2-(m-Methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-2-(3-methoxyphenyl)piperazine; Boc-2-(3-MeO-Ph)-piperazine
EINECS	Contact for details

Quality Control

Our 2-(3-Methoxy-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.