Description

4-Boc-2-(4-(Trifluoromethyl)Phenyl)Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and protective Boc (tert-butoxycarbonyl) group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in CNS and oncology research.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides due to its structural complexity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and structure-activity relationship (SAR) studies.
• Peptidomimetics: Acts as a non-peptide backbone mimic in the design of peptide-like therapeutic compounds.
• Ligand Development: Utilized for constructing specialized ligands in catalysis and receptor binding studies.

Basic Information

Product Name	4-Boc-2-(4-(Trifluoromethyl)Phenyl)Piperazine
CAS No.	886767-93-7
Molecular Formula	C16H21F3N2O2
Molecular Weight	330.35 g/mol
Synonyms	1-Boc-2-(4-(Trifluoromethyl)phenyl)piperazine; tert-Butyl 2-[4-(trifluoromethyl)phenyl]piperazine-1-carboxylate; 2-(4-Trifluoromethylphenyl)-1-piperazinecarboxylic acid tert-butyl ester; 4-Boc-2-(4-Trifluoromethylphenyl)piperazine; 1-(tert-Butoxycarbonyl)-2-(4-(trifluoromethyl)phenyl)piperazine; N-Boc-2-(4-Trifluoromethylphenyl)piperazine; 886767-93-7
EINECS	Contact for details

Quality Control

Our 4-Boc-2-(4-(Trifluoromethyl)Phenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.