Description

tert-Butyl 3-(4-Bromophenyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for medicinal chemistry research and pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Scaffold: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its piperazine core and bromophenyl handle for further functionalization.
• Ligand Synthesis: Employed in the development of novel ligands for biological receptors and enzymes.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and pesticides.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes to study biological pathways.

Basic Information

Product Name	tert-Butyl 3-(4-Bromophenyl)Piperazine-1-Carboxylate
CAS No.	886767-69-7
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	1-Boc-3-(4-bromophenyl)piperazine; tert-Butyl 3-(4-bromophenyl)-1-piperazinecarboxylate; 3-(4-Bromophenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(4-bromophenyl)piperazine; Boc-3-(4-Bromophenyl)piperazine; 886767-69-7; 3-(p-Bromophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4-Bromophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.