Description

1-Boc-2-(3-Bromophenyl)Piperazine is a high-purity, advanced pharmaceutical intermediate and building block used in modern organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex molecules with specific biological activity. It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the development of novel therapeutic compounds.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to create diverse libraries of compounds for biological testing.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Boc-2-(3-Bromophenyl)Piperazine
CAS No.	886767-65-3
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	tert-Butyl 2-(3-bromophenyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-(3-bromophenyl)piperazine; 2-(3-Bromophenyl)-1-Boc-piperazine; 1-Boc-2-(3-Bromophenyl)piperazine; N-Boc-2-(3-Bromophenyl)piperazine; 1-(tert-Butyloxycarbonyl)-2-(3-bromophenyl)piperazine; 2-(3-Bromophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-2-(3-Bromophenyl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.