Description

3-(4-Chlorophenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile building block for synthesizing complex molecules, particularly in the creation of bioactive compounds targeting the central nervous system. It is essential for research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with neurological activity.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new APIs requiring a functionalized piperazine core.
• Chemical Research & Development: Serves as a critical reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand Synthesis: Employed in the preparation of specialized ligands for biochemical assays and receptor studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	3-(4-Chlorophenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886767-49-3
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	tert-Butyl 3-(4-chlorophenyl)piperazine-1-carboxylate; 1-Boc-3-(4-chlorophenyl)piperazine; 3-(p-Chlorophenyl)-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 3-(4-Chlorophenyl)-1-Boc-piperazine; N-Boc-3-(4-chlorophenyl)piperazine; 1-(tert-Butoxycarbonyl)-3-(4-chlorophenyl)piperazine; 886767-49-3; 3-(4-Chlorophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.