Description

2-(3-Chloro-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel psychoactive substances (NPS) and other therapeutic agents targeting serotonin and dopamine receptors.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides due to its piperazine core structure.
• Chemical Synthesis Building Block: Employed in organic chemistry research for constructing complex heterocyclic compounds and for introducing the tert-butyloxycarbonyl (Boc) protected piperazine moiety.
• Life Science Research: Utilized in academic and industrial R&D for pharmacological studies and as a reference standard in analytical method development.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.

Basic Information

Product Name	2-(3-Chloro-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	886767-45-9
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	1-Boc-2-(3-Chlorophenyl)piperazine; tert-Butyl 2-(3-chlorophenyl)piperazine-1-carboxylate; 2-(3-Chlorophenyl)-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-2-(3-chlorophenyl)piperazine; 2-(3-Chlorophenyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-2-(3-Chlorophenyl)piperazine; 886767-45-9; 2-(3-Chloro-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 2-(3-Chloro-Phenyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.