Description

1-Boc-3-m-Tolylpiperazine is a high-purity, protected piperazine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive nitrogen-containing scaffold for constructing complex pharmaceutical molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the development of new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology drug candidates.
• Peptidomimetic Chemistry: Used to introduce constrained piperazine moieties into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a chelating ligand precursor for metal complexes used in catalysis and materials science.
• Agrochemical Research: Employed in the discovery and development of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Utilized to create tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	1-Boc-3-m-Tolylpiperazine
CAS No.	886766-73-0
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	1-Boc-3-(3-Methylphenyl)piperazine; tert-Butyl 3-(3-methylphenyl)piperazine-1-carboxylate; 3-m-Tolyl-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(3-methylphenyl)piperazine; 1-N-Boc-3-(3-methylphenyl)piperazine; 886766-73-0; BOC-m-Tolylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-3-m-Tolylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to relevant industry standards for advanced intermediates, supporting our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.