Description

1-[2-(Trifluoromethoxy)Benzyl]Piperazine is a high-value, synthetically versatile piperazine derivative featuring a benzyl group substituted with a trifluoromethoxy moiety. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling the introduction of specific steric and electronic properties to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A requested component for custom chemical synthesis services catering to biotechnology and pharmaceutical clients.

Basic Information

Product Name	1-[2-(Trifluoromethoxy)Benzyl]Piperazine
CAS No.	886762-54-5
Molecular Formula	C13H15F3N2O
Molecular Weight	272.27 g/mol
Synonyms	1-[(2-Trifluoromethoxy)phenyl]methyl]piperazine; 1-[[2-(Trifluoromethoxy)phenyl]methyl]piperazine; 2-((Trifluoromethoxy)benzyl)piperazine; 1-(2-Trifluoromethoxybenzyl)piperazine; α-(2-Trifluoromethoxyphenyl)-1-piperazinemethane; Piperazine, 1-[[2-(trifluoromethoxy)phenyl]methyl]-; 886762-54-5
EINECS	Contact for details

Quality Control

Our 1-[2-(Trifluoromethoxy)Benzyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.