Description

2,3-Dichloro-6-(Trifluoromethyl)Benzoyl Chloride is a high-purity, multi-functional aromatic acid chloride building block. This compound is valued for its unique trifluoromethyl and dual chloro substituents, which impart significant electronic and steric properties for advanced synthesis. It is primarily sought after by R&D and process development chemists in the pharmaceutical and agrochemical industries for constructing complex active ingredients. Its reactivity makes it a critical intermediate for creating novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and polymers for advanced materials, such as liquid crystals and high-performance polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,3-Dichloro-6-(Trifluoromethyl)Benzoyl Chloride
CAS No.	886501-87-7
Molecular Formula	C8H2Cl3F3O
Molecular Weight	277.45 g/mol
Synonyms	2,3-Dichloro-6-(trifluoromethyl)benzoyl chloride; 2,3-Dichloro-alpha,alpha,α-trifluoro-p-toluoyl chloride; 2,3-Dichloro-α,α,α-trifluoro-p-toluoyl chloride; Benzoyl chloride, 2,3-dichloro-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2,3-dichlorobenzoyl chloride; 2,3-Dichloro-6-trifluoromethylbenzoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dichloro-6-(Trifluoromethyl)Benzoyl Chloride is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.