Description

(4-Amino-Piperidin-1-Yl)-(3-Chloro-Phenyl)-Methanone is a high-purity, functionalized piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and pharmacophore in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and agrochemical intermediates.
• Academic Research: Utilized in universities and research institutes for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	(4-Amino-Piperidin-1-Yl)-(3-Chloro-Phenyl)-Methanone
CAS No.	886497-87-6
Molecular Formula	C12H15ClN2O
Molecular Weight	238.72 g/mol
Synonyms	1-[(3-Chlorophenyl)carbonyl]-4-piperidinamine; (3-Chlorophenyl)(4-aminopiperidin-1-yl)methanone; 4-Amino-1-(3-chlorobenzoyl)piperidine; 4-Amino-1-(3-chlorobenzoyl)piperidine; 886497-87-6; (4-Aminopiperidin-1-yl)(3-chlorophenyl)methanone; 1-(3-Chlorobenzoyl)piperidin-4-amine
EINECS	Contact for details

Quality Control

Our (4-Amino-Piperidin-1-Yl)-(3-Chloro-Phenyl)-Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.