Description

2-Methyl-3-(4-Boc-Piperazin-1-Yl)-Propionic Acid Methyl Ester is a high-value, protected piperazine derivative ester used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this intermediate for its versatility in introducing functionalized piperazine moieties under mild conditions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in central nervous system (CNS) and oncology research.
• Protease Inhibitor Synthesis: Used in the construction of protease inhibitor scaffolds for antiviral and therapeutic applications.
• Peptidomimetic Chemistry: Serves as a crucial component in the design and synthesis of peptidomimetics and constrained peptides.
• Agrochemical Active Ingredient Development: Intermediate in the synthesis of novel agrochemicals requiring functionalized heterocyclic systems.
• Ligand and Catalyst Preparation: Useful for creating specialized ligands and organocatalysts for asymmetric synthesis.
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRAM) for producing bespoke fine chemicals.

Basic Information

Product Name	2-Methyl-3-(4-Boc-Piperazin-1-Yl)-Propionic Acid Methyl Ester
CAS No.	886366-38-7
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	Methyl 2-Methyl-3-(4-(tert-butoxycarbonyl)piperazin-1-yl)propanoate; 1-Boc-4-(2-Methoxycarbonylpropyl)piperazine; 3-(4-Boc-Piperazin-1-yl)-2-Methylpropionic Acid Methyl Ester; tert-Butyl 4-(2-methoxycarbonylpropyl)piperazine-1-carboxylate; 886366-38-7; Boc-Pip-Prop-OMe; N-Boc-4-(2-Methoxycarbonylpropyl)piperazine
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(4-Boc-Piperazin-1-Yl)-Propionic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) are provided with every shipment, detailing purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.