Description

3-Cyano-1-n-Fmoc-Piperidine is a high-purity, protected piperidine derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, offering both a reactive nitrile group and an Fmoc-protected amine, enabling precise and sequential synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel active pharmaceutical ingredients (APIs) and complex peptide-based therapeutics.

Application

• Pharmaceutical Intermediates: A key synthon for constructing piperidine-containing drug candidates, including central nervous system (CNS) agents and enzyme inhibitors.
• Peptide Synthesis (Solid-Phase): Serves as a protected amino acid derivative for the controlled incorporation of modified piperidine structures into peptide chains.
• Combinatorial Chemistry: Used in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged molecules for studying biological pathways and target engagement.
• Agrochemical Research: Acts as a precursor in the development of novel crop protection agents with specific biological activity.
• Material Science: Potential monomer or precursor for advanced polymers and functional materials with tailored properties.

Basic Information

Product Name	3-Cyano-1-n-Fmoc-Piperidine
CAS No.	886362-86-3
Molecular Formula	C22H22N2O2
Molecular Weight	346.43 g/mol
Synonyms	1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-cyanopiperidine; 1-Fmoc-3-cyanopiperidine; 3-Cyano-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperidine; 1-N-Fmoc-3-cyanopiperidine; N-Fmoc-3-cyano-piperidine; Fmoc-3-CNP; Piperidine, 3-cyano-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-; 886362-86-3
EINECS	Contact for details

Quality Control

Every batch of 3-Cyano-1-n-Fmoc-Piperidine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with the standards required for cGMP and non-GMP pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.