Description

3-(2-Carboxy-Acetyl)-Piperidine-1-Carboxylic Acid Benzyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and metabolic disorder therapeutics. It is primarily utilized by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of piperidine-based drug candidates targeting neurological pathways.
• Custom Chemical Manufacturing: Employed in contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke molecules for clinical trials.
• Protease Inhibitor Research: Used in the research and development of enzyme inhibitors due to its specific carboxy-acetyl functional group.
• Peptidomimetic Chemistry: Acts as a scaffold in the design of peptide mimics for enhanced bioavailability and metabolic stability.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs in both academic laboratories and industrial R&D departments.
• Process Development & Scale-Up: Supports route scouting and optimization studies for the efficient, large-scale production of target molecules.

Basic Information

Product Name	3-(2-Carboxy-Acetyl)-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	886362-40-9
Molecular Formula	C16H19NO5
Molecular Weight	305.33 g/mol
Synonyms	1-Benzyl 3-(2-Carboxyacetyl)piperidine-1-carboxylate; Benzyl 3-(2-Carboxyacetyl)piperidine-1-carboxylate; 1-Carbobenzyloxy-3-(2-carboxyacetyl)piperidine; 3-(2-Carboxyacetyl)-1-(benzyloxycarbonyl)piperidine; 886362-40-9; 3-(Carboxyacetyl)-1-CBZ-piperidine; 1-CBZ-3-(2-Carboxyacetyl)piperidine; Piperidine-1-carboxylic acid, 3-(2-carboxyacetyl)-, benzyl ester
EINECS	Contact for details

Quality Control

Our production of 3-(2-Carboxy-Acetyl)-Piperidine-1-Carboxylic Acid Benzyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and cGMP manufacturing. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.