Description

3-n-Boc-Amino-3-(3'-Cbz)Piperidine-Propionic Acid Ethyl Ester is a sophisticated, bifunctionalized piperidine derivative that serves as a critical building block in modern organic synthesis. Its value lies in providing a protected amine and carboxylic acid functionality, enabling precise and sequential coupling reactions for the construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical industry, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Peptidomimetic Synthesis: Used to incorporate constrained, non-natural amino acid motifs into peptide backbones to enhance stability and biological activity.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a versatile scaffold for the introduction of diverse functional groups.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of advanced intermediates for clients.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of focused chemical libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	3-n-Boc-Amino-3-(3'-Cbz)Piperidine-Propionic Acid Ethyl Ester
CAS No.	886362-36-3
Molecular Formula	C24H36N2O6
Molecular Weight	448.56 g/mol
Synonyms	Ethyl 3-[(tert-butoxycarbonyl)amino]-3-[(benzyloxycarbonyl)amino]piperidine-1-propanoate; 1-(2-Ethoxy-2-oxoethyl)-3-{[(benzyloxy)carbonyl]amino}-3-{[(tert-butoxy)carbonyl]amino}piperidin-1-ium; 3-(Boc-amino)-3-(Cbz-amino)piperidine-1-propionic acid ethyl ester; 3-N-Boc-amino-3-N-Cbz-piperidine propionic acid ethyl ester; 3-(N-Boc-amino)-3-(N-Cbz-amino)piperidine-1-propionic acid ethyl ester; Bifunctionalized Piperidine Ester; Boc-Cbz Piperidine Propionate Ester
EINECS	Contact for details

Quality Control

Our 3-n-Boc-Amino-3-(3'-Cbz)Piperidine-Propionic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and cGMP manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, providing our partners with the documentation necessary for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.