Description

tert-Butyl 4-(3-Acetyl-4-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for B2B buyers who require reliable, high-quality building blocks for complex organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry and process development, where precise molecular architecture and consistent purity are non-negotiable for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas requiring complex nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies, enabling the exploration of new chemical entities in academic and industrial R&D laboratories.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential APIs, where its defined purity and stability are essential for reproducible manufacturing processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services to the pharmaceutical industry.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	tert-Butyl 4-(3-Acetyl-4-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	886361-04-2
Molecular Formula	C17H23N3O5
Molecular Weight	349.38 g/mol
Synonyms	1,2,3,6-Tetrahydro-1(2H)-pyrazinecarboxylic acid, 4-(3-acetyl-4-nitrophenyl)-, 1,1-dimethylethyl ester; tert-Butyl 4-(3-acetyl-4-nitrophenyl)-1,2,3,6-tetrahydro-1(2H)-pyrazinecarboxylate; 4-(3-Acetyl-4-nitrophenyl)tetrahydro-1(2H)-pyrazinecarboxylic acid tert-butyl ester; 886361-04-2; tert-Butyl 4-(3-acetyl-4-nitrophenyl)-1,2,3,6-tetrahydro-2H-pyrazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Acetyl-4-Nitrophenyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' needs for reliable material in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.