Description

tert-Butyl 4-(1-benzylpyrrolidin-3-yl)piperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound serves as a critical building block for the synthesis of complex molecules, particularly in the creation of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• CNS Drug Development: Particularly valuable for constructing molecules targeting neurological receptors and pathways due to its piperazine-pyrrolidine scaffold.
• Custom Synthesis: Serves as a starting material or intermediate for contract research and custom manufacturing projects.
• Process Chemistry & Scale-Up: Employed in route scouting and process optimization for the commercial-scale production of target molecules.
• Chemical Library Synthesis: Used to generate diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	tert-Butyl 4-(1-benzylpyrrolidin-3-yl)piperazine-1-carboxylate
CAS No.	885959-04-6
Molecular Formula	C20H31N3O2
Molecular Weight	345.48 g/mol
Synonyms	1-Boc-4-(1-benzyl-3-pyrrolidinyl)piperazine; tert-Butyl 4-[1-(phenylmethyl)-3-pyrrolidinyl]-1-piperazinecarboxylate; 4-(1-Benzylpyrrolidin-3-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-Piperazinecarboxylic acid, 4-[1-(phenylmethyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl ester; 885959-04-6; BOC-4-(1-Benzyl-3-pyrrolidinyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1-benzylpyrrolidin-3-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.