Description

Ethyl 1-(4-Formyl-2-Nitrophenyl)-4-Piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct nitrophenyl and formyl functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new bioactive molecules.
• Organic Synthesis: Serves as a versatile precursor for constructing piperidine-containing heterocycles and other complex organic frameworks.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional laboratories for advanced organic synthesis and chemical methodology development.

Basic Information

Product Name	Ethyl 1-(4-Formyl-2-Nitrophenyl)-4-Piperidinecarboxylate
CAS No.	885949-64-4
Molecular Formula	C15H18N2O5
Molecular Weight	306.32 g/mol
Synonyms	Ethyl 4-(4-formyl-2-nitrophenyl)piperidine-1-carboxylate; 1-(4-Formyl-2-nitrophenyl)-4-piperidinecarboxylic acid ethyl ester; 4-Piperidinecarboxylic acid, 1-(4-formyl-2-nitrophenyl)-, ethyl ester; 885949-64-4; Ethyl 1-(4-formyl-2-nitrophenyl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 1-(4-Formyl-2-Nitrophenyl)-4-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.