Description

2-Chloro-6-(4-Methyl-1-Piperidinyl)Pyrazine is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its core value lies in its unique molecular scaffold, which combines a halogenated pyrazine ring with a substituted piperidine moiety, enabling precise structural modifications for drug discovery. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and antimicrobial agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a sophisticated ligand in organometallic chemistry and catalysis due to the nitrogen-rich, chelating pyrazine core.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular semiconductors.
• Chemical Biology Probe: Utilized as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloro-6-(4-Methyl-1-Piperidinyl)Pyrazine
CAS No.	885704-66-5
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	2-Chloro-6-(4-methylpiperidin-1-yl)pyrazine; 6-Chloro-3-(4-methyl-1-piperidinyl)pyrazine; 2-Chloro-6-(4-methyl-1-piperazinyl)pyrazine (common misnomer); 2-Chloro-6-(4-methylpiperidino)pyrazine; Pyrazine, 2-chloro-6-(4-methyl-1-piperidinyl)-; 885704-66-5; 2-Chloro-6-(4-methylpiperidin-1-yl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(4-Methyl-1-Piperidinyl)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.