Description

1-Thiazol-2-Ylmethyl-Piperazine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole-piperazine scaffold imparts valuable biological activity. Pharmaceutical R&D teams and fine chemical manufacturers need it to create next-generation therapeutic agents targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides due to the bioactive thiazole moiety.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a molecular probe or scaffold in the study of enzyme inhibition and receptor-ligand interactions.
• Material Science: Potential intermediate for the synthesis of functional polymers and advanced organic electronic materials.

Basic Information

Product Name	1-Thiazol-2-Ylmethyl-Piperazine
CAS No.	885699-90-1
Molecular Formula	C9H13N3S
Molecular Weight	195.28 g/mol
Synonyms	1-[(Thiazol-2-yl)methyl]piperazine; 2-(Piperazin-1-ylmethyl)thiazole; Piperazine, 1-[(2-thiazolyl)methyl]-; 1-(Thiazol-2-ylmethyl)piperazine; 885699-90-1; Thiazol-2-ylmethyl-piperazine; 1-(Thiazolylmethyl)piperazine; 2-Piperazin-1-ylmethyl-thiazole
EINECS	Contact for details

Quality Control

Our 1-Thiazol-2-Ylmethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.