Description

tert-Butyl 4-(2-Cyanopropan-2-yl)piperazine-1-carboxylate is a high-value, protected piperazine derivative featuring a nitrile functional group. This compound serves as a critical pharmaceutical intermediate and versatile organic building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and library synthesis due to its reactive nitrile and protected amine functionalities.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides.
• Ligand Synthesis: Preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals.

Basic Information

Product Name	tert-Butyl 4-(2-Cyanopropan-2-yl)piperazine-1-carboxylate
CAS No.	885698-82-8
Molecular Formula	C13H23N3O2
Molecular Weight	253.34 g/mol
Synonyms	1-Boc-4-(2-cyano-2-propyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-cyano-2-propyl)piperazine; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-methylpropanenitrile; tert-Butyl 4-(1-cyano-1-methylethyl)piperazine-1-carboxylate; 2-Methyl-2-(4-((tert-butoxycarbonyl)amino)piperidin-1-yl)propanenitrile (related); BOC-Piperazine-CN derivative; 885698-82-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Cyanopropan-2-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This material may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.