Description

1-[3-(Benzoyloxy)Propyl]-2,3-Dihydro-5-[(2R)-2-[[2-[2-(2,2,2-Trifluoroethoxy)Phenoxy]Ethyl]Amino]Propyl]-1H-Indole-7-Carbonitrile Ethanedioate is a high-purity, complex organic salt with a defined stereochemistry, designed for advanced research and development. This compound is valued for its specific molecular architecture, which makes it a critical intermediate or reference standard in sophisticated synthetic pathways. It is primarily sought by pharmaceutical R&D teams, biotechnology firms, and advanced material scientists working on novel active pharmaceutical ingredients (APIs) and receptor-targeted molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) or cardiovascular research.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies, enzyme inhibition assays, and receptor binding experiments.
• Process Development & Scale-up: Employed in process chemistry for route scouting, optimization, and the production of non-commercialized candidate drugs during clinical trials.
• Analytical Standard: Provides a high-purity benchmark for method development and validation in quality control laboratories using HPLC, LC-MS, or NMR.
• Academic Research: Utilized in university and institutional labs for cutting-edge organic chemistry and medicinal chemistry projects.
• Custom Synthesis Starting Material: Acts as a precursor for the custom synthesis of more complex, proprietary compounds for client-specific applications.

Basic Information

Product Name	1-[3-(Benzoyloxy)Propyl]-2,3-Dihydro-5-[(2R)-2-[[2-[2-(2,2,2-Trifluoroethoxy)Phenoxy]Ethyl]Amino]Propyl]-1H-Indole-7-Carbonitrile Ethanedioate
CAS No.	885340-12-5
Molecular Formula	C34H34F3N3O6
Molecular Weight	637.65 g/mol
Synonyms	5-[(2R)-2-({2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl}amino)propyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile ethanedioate; (R)-1-[3-(Benzoyloxy)Propyl]-5-[2-[[2-[2-(2,2,2-Trifluoroethoxy)Phenoxy]Ethyl]Amino]Propyl]Indoline-7-Carbonitrile Oxalate; UNII-7QO2L6K2QH; 7QO2L6K2QH; TAK-438 Intermediate; Vonoprazan Fumarate Related Compound; (R)-Vonoprazan Impurity
EINECS	Contact for details

Quality Control

Our production of 1-[3-(Benzoyloxy)Propyl]-2,3-Dihydro-5-[(2R)-2-[[2-[2-(2,2,2-Trifluoroethoxy)Phenoxy]Ethyl]Amino]Propyl]-1H-Indole-7-Carbonitrile Ethanedioate adheres to stringent quality management systems. The material is manufactured and controlled under a cGMP-compliant environment suitable for pharmaceutical development. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure identity, potency, and purity. Certificates of Analysis (COA) detailing batch-specific results are provided and traceability is maintained for full supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (R-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.