Description

7-(tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group and a carboxylic acid handle, making it a versatile building block for complex molecule synthesis. This compound is critical for medicinal chemistry research and development, particularly in the construction of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with imidazopyrazine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for creating peptide-like molecules with enhanced metabolic stability.
• API Development: Integral component in multi-step synthetic routes for producing Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for contract manufacturing and custom synthesis projects.

Basic Information

Product Name	7-(tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-2-Carboxylic Acid
CAS No.	885281-30-1
Molecular Formula	C12H17N3O4
Molecular Weight	267.28 g/mol
Synonyms	Boc-THIP-COOH; 2-Imidazo[1,2-a]pyrazinecarboxylic acid, 5,6,7,8-tetrahydro-7-[(1,1-dimethylethoxy)carbonyl]-; 7-Boc-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid; 7-(Boc)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid; tert-Butyl 2-carboxy-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; 7-N-Boc-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-(tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.