Description

1-Cbz-3,3-Dimethyl-Piperazine is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Peptidomimetic Chemistry: Used in the synthesis of peptide analogs and mimetics, where the Cbz-protected amine and rigid piperazine core introduce specific conformational and functional properties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require complex amine-containing heterocycles.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and the exploration of new chemical space.

Basic Information

Product Name	1-Cbz-3,3-Dimethyl-Piperazine
CAS No.	885278-86-4
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3,3-dimethylpiperazine; N-Carbobenzoxy-3,3-dimethylpiperazine; 1-Cbz-3,3-dimethylpiperazine; N-Cbz-3,3-dimethylpiperazine; 3,3-Dimethyl-1-(phenylmethoxy)carbonylpiperazine; 1-(Benzyloxycarbonyl)-3,3-dimethylpiperazine; Piperazine, 1-[(phenylmethoxy)carbonyl]-3,3-dimethyl-
EINECS	Contact for details

Quality Control

Our 1-Cbz-3,3-Dimethyl-Piperazine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.