Description

1-Cbz-3,5-Dimethyl-Piperazine is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• API Synthesis: Used in the multi-step synthesis of complex molecules where a protected, substituted piperazine core is required.
• Peptidomimetics & Bioconjugation: Employed in the design and synthesis of peptide analogs and for creating bioconjugates due to its reactive amine functionality (after deprotection).
• Agrochemical Research: Acts as a building block for developing novel crop protection agents and herbicides.
• Ligand & Catalyst Development: Useful in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Scale-Up: Supplied for custom chemical synthesis projects from laboratory to pilot plant scale.

Basic Information

Product Name	1-Cbz-3,5-Dimethyl-Piperazine
CAS No.	885278-83-1
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3,5-dimethylpiperazine; 3,5-Dimethyl-1-Cbz-piperazine; 1-Carbobenzoxy-3,5-dimethylpiperazine; N-Carbobenzyloxy-3,5-dimethylpiperazine; 1-(Benzyloxycarbonyl)-3,5-dimethylpiperazine; 3,5-Dimethylpiperazine-1-carboxylic acid benzyl ester; Piperazine-1-carboxylic acid, 3,5-dimethyl-, benzyl ester
EINECS	Contact for details

Quality Control

Our 1-Cbz-3,5-Dimethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.