Description

Benzofuran-2-Yl-[4-(4-Chloro-Phenyl)-Piperazin-1-Yl]-Acetic Acid CAS NO 885277-00-9 is a high-purity, synthetically derived organic compound featuring a benzofuran core linked to a chlorophenyl-piperazine moiety via an acetic acid bridge. This specific molecular architecture makes it a critical intermediate for advanced research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop compounds with potential receptor-binding activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Employed in vitro studies to investigate biological pathways and enzyme interactions.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial fine chemicals and APIs.

Basic Information

Product Name	Benzofuran-2-Yl-[4-(4-Chloro-Phenyl)-Piperazin-1-Yl]-Acetic Acid
CAS No.	885277-00-9
Molecular Formula	C22H21ClN2O3
Molecular Weight	396.87 g/mol
Synonyms	2-[4-(4-Chlorophenyl)piperazin-1-yl]-2-(2-benzofuranyl)acetic acid; {[4-(4-Chlorophenyl)piperazin-1-yl](2-benzofuran-2-yl)}acetic acid; Benzofuran-2-yl[4-(4-chlorophenyl)piperazin-1-yl]acetic acid; 885277-00-9; BCPPA; 1-(4-Chlorophenyl)-4-[(2-benzofuranyl)acetyl]piperazine
EINECS	Contact for details

Quality Control

Every batch of our Benzofuran-2-Yl-[4-(4-Chloro-Phenyl)-Piperazin-1-Yl]-Acetic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports cGMP compliance for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.