Description

[4-(4-Chloro-Phenyl)-Piperazin-1-Yl]-Pyridin-3-Yl-Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Biochemical Research: Used as a reference standard and ligand in pharmacological studies for receptor binding assays.
• Organic Synthesis: Serves as a versatile building block for constructing complex piperazine- and pyridine-containing molecular architectures.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	[4-(4-Chloro-Phenyl)-Piperazin-1-Yl]-Pyridin-3-Yl-Acetic Acid
CAS No.	885276-88-0
Molecular Formula	C17H18ClN3O2
Molecular Weight	331.80 g/mol
Synonyms	2-([4-(4-Chlorophenyl)piperazin-1-yl]methyl)pyridin-3-ylacetic acid; 3-[[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-2-pyridine]acetic Acid; 4-(4-Chlorophenyl)-1-[(3-carboxymethyl-2-pyridyl)methyl]piperazine; (3-((4-(4-Chlorophenyl)piperazin-1-yl)methyl)pyridin-2-yl)acetic acid; 885276-88-0; 4-(4-Chloro-Phenyl)-Piperazin-1-Yl-Pyridin-3-Yl-Acetic Acid
EINECS	Contact for details

Quality Control

Our [4-(4-Chloro-Phenyl)-Piperazin-1-Yl]-Pyridin-3-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.