Description

(3-Boc-Amino-Piperidin-1-Yl)-Naphthalen-2-Yl-Acetic Acid CAS NO 885276-52-8 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold protected by a tert-butoxycarbonyl (Boc) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of therapeutic agents targeting the central nervous system, oncology, and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Development: The piperidine-Boc structure is valuable for creating inhibitors of various proteolytic enzymes.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog in the design of peptide-like molecules with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and niche APIs.

Basic Information

Product Name	(3-Boc-Amino-Piperidin-1-Yl)-Naphthalen-2-Yl-Acetic Acid
CAS No.	885276-52-8
Molecular Formula	C22H28N2O4
Molecular Weight	384.47 g/mol
Synonyms	2-[(3-{[(tert-Butoxy)carbonyl]amino}-1-piperidinyl)]-2-naphthaleneacetic Acid; 2-(3-((tert-Butoxycarbonyl)amino)piperidin-1-yl)-2-naphthylacetic Acid; 2-(3-Boc-aminopiperidin-1-yl)-2-naphthylacetic Acid; 2-(3-(Boc-amino)piperidin-1-yl)naphthalene-2-acetic Acid; (3-Boc-Aminopiperidin-1-yl)-Naphthalen-2-yl-Acetic Acid; 2-(3-((tert-Butoxycarbonyl)amino)piperidin-1-yl)naphthalene-2-acetic Acid; N-Boc-3-amino-1-(2-carboxymethylnaphthyl)piperidine; 885276-52-8
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Piperidin-1-Yl)-Naphthalen-2-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.