Description

(3-n-Boc-Amino-Piperidin-1-Yl)-p-Tolyl-Acetic Acid CAS NO 885276-43-7 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold protected by a tert-butoxycarbonyl (Boc) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing therapeutics targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting G-protein-coupled receptors (GPCRs).
• Protease Inhibitor Development: Used in research for creating inhibitors for various protease enzymes.
• Peptidomimetic Chemistry: Serves as a crucial component in the design and synthesis of peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Industrial R&D: Essential for exploratory research in medicinal chemistry within academic institutions and industrial R&D laboratories.

Basic Information

Product Name	(3-n-Boc-Amino-Piperidin-1-Yl)-p-Tolyl-Acetic Acid
CAS No.	885276-43-7
Molecular Formula	C19H28N2O4
Molecular Weight	348.44 g/mol
Synonyms	1-[(4-Methylphenyl)acetyl]-3-[(tert-butoxycarbonyl)amino]piperidine; 3-[(tert-Butoxycarbonyl)amino]-1-[(4-methylphenyl)acetyl]piperidine; 3-(Boc-amino)-1-(p-tolylacetyl)piperidine; (3-((tert-Butoxycarbonyl)amino)piperidin-1-yl)(p-tolyl)acetic acid; Boc-3-amino-1-(p-tolylacetyl)piperidine; 885276-43-7; BOC-PIPERIDINE-ACETIC ACID DERIVATIVE
EINECS	Contact for details

Quality Control

Our (3-n-Boc-Amino-Piperidin-1-Yl)-p-Tolyl-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for advanced research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.