Description

1-Boc-4-(Carboxy-Naphthalen-2-Yl-Methyl)-[1,4]Diazepane is a high-purity, advanced pharmaceutical intermediate featuring a protected diazepane core linked to a naphthalene carboxylic acid moiety. This compound is critically important for enabling the synthesis of complex, biologically active molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by research institutions and pharmaceutical companies developing novel therapeutics, where it serves as a key building block for creating potential drug candidates with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with modified pharmacokinetic profiles.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for creating peptidomimetics and other bioactive compounds that mimic peptide structures.
• Chemical Biology Probes: Employed in the development of specialized molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	1-Boc-4-(Carboxy-Naphthalen-2-Yl-Methyl)-[1,4]Diazepane
CAS No.	885275-74-1
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	1-Boc-4-[(2-Naphthoyl)methyl]-1,4-diazepane; tert-Butyl 4-[(2-naphthoyl)methyl]-1,4-diazepane-1-carboxylate; 1,4-Diazepane-1-carboxylic acid, 4-[(2-naphthoyl)methyl]-, 1,1-dimethylethyl ester; 4-[(2-Naphthoyl)methyl]-1,4-diazepane-1-carboxylic acid tert-butyl ester; 1-Boc-4-(2-naphthoylmethyl)-1,4-diazepane; Boc-Protected Naphthalene Diazepane Carboxylate
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(Carboxy-Naphthalen-2-Yl-Methyl)-[1,4]Diazepane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.