Description

1-Boc-4-(Carboxy-Pyridin-3-Yl-Methyl)-[1,4]Diazepane is a high-purity, advanced pharmaceutical intermediate featuring a protected diazepane scaffold with a functionalized pyridine moiety. This compound is critically important for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents, including potential candidates for neurological and oncological applications.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and bioactive compounds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the development and scale-up production of Active Pharmaceutical Ingredients (APIs), especially those targeting specific receptor sites.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services catering to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	1-Boc-4-(Carboxy-Pyridin-3-Yl-Methyl)-[1,4]Diazepane
CAS No.	885275-68-3
Molecular Formula	C18H25N3O4
Molecular Weight	347.41 g/mol
Synonyms	1-Boc-4-[(3-Pyridinylcarbonyl)methyl]-1,4-diazepane; tert-Butyl 4-[(pyridine-3-carbonyl)methyl]-1,4-diazepane-1-carboxylate; 1,4-Diazepane-1-carboxylic acid, 4-[(3-pyridinylcarbonyl)methyl]-, 1,1-dimethylethyl ester; 4-[(3-Pyridinylcarbonyl)methyl]-1,4-diazepane-1-carboxylic acid tert-butyl ester; 1-Boc-4-(3-Pyridinecarbonylmethyl)-1,4-diazepane; Boc-Protected 4-(3-Pyridylcarbonylmethyl)diazepane
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(Carboxy-Pyridin-3-Yl-Methyl)-[1,4]Diazepane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.