Description

4-(Carboxy-p-Tolyl-Methyl)-[1,4]Diazepane-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected diazepane derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel pharmaceutical candidates, particularly in the areas of central nervous system (CNS) and metabolic disease therapeutics. Its specific structure makes it a valuable intermediate for constructing complex molecules with targeted biological activity, serving the needs of pharmaceutical R&D and fine chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Synthesis: Serves as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability.
• Ligand Development: Employed in the creation of specialized ligands for receptors and enzymes within biochemical research.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client programs.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and bioorganic chemistry.

Basic Information

Item	Details
Product Name	4-(Carboxy-p-Tolyl-Methyl)-[1,4]Diazepane-1-Carboxylic Acid tert-Butyl Ester
CAS No.	885275-67-2
Molecular Formula	C20H28N2O4
Molecular Weight	360.45 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-[(4-methylphenyl)(carboxy)methyl]-1,4-diazepane; 4-[(4-Methylphenyl)(carboxy)methyl]-1,4-diazepane-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(4-methylphenyl)(carboxy)methyl]-1,4-diazepane-1-carboxylate; 4-(Carboxy-p-tolyl-methyl)-1,4-diazepane-1-carboxylic acid tert-butyl ester; 1,4-Diazepane-1-carboxylic acid, 4-[(4-methylphenyl)(carboxy)methyl]-, 1,1-dimethylethyl ester; BOC-Protected Diazepane Derivative; 885275-67-2
EINECS	Contact for details

Quality Control

Our 4-(Carboxy-p-Tolyl-Methyl)-[1,4]Diazepane-1-Carboxylic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.