Description

1-Boc-4-(Benzofuran-2-Yl-Carboxy-Methyl)-Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a tert-butoxycarbonyl (Boc) group and functionalized with a benzofuran carboxylic acid derivative. This compound is critical for medicinal chemistry research and development, providing a versatile scaffold for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential protease inhibitors due to its piperazine-based structure.
• CNS Drug Candidates: Employed in the development of compounds targeting neurological disorders and psychiatric conditions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Academic & Institutional Research: Used in university and institutional labs for fundamental chemical biology and synthetic methodology studies.

Basic Information

Product Name	1-Boc-4-(Benzofuran-2-Yl-Carboxy-Methyl)-Piperazine
CAS No.	885275-63-8
Molecular Formula	C20H26N2O5
Molecular Weight	374.43 g/mol
Synonyms	1-Boc-4-[(benzofuran-2-carbonyl)methyl]piperazine; 1-(tert-Butoxycarbonyl)-4-[(1-benzofuran-2-ylcarbonyl)methyl]piperazine; tert-Butyl 4-[(1-benzofuran-2-ylcarbonyl)methyl]piperazine-1-carboxylate; 4-[(Benzofuran-2-carbonyl)methyl]-1-Boc-piperazine; Piperazine, 1-[(1,1-dimethylethoxy)carbonyl]-4-[(2-benzofuranylcarbonyl)methyl]-; 885275-63-8; 1-Boc-4-(Benzofuran-2-Carboxymethyl)Piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(Benzofuran-2-Yl-Carboxy-Methyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for advanced research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.