Description

3-Hydroxymethyl-Piperazine-1-Carboxylic Acid Allyl Ester is a versatile and high-value piperazine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a reactive hydroxymethyl group and a protected carboxylic acid moiety, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of piperazine-based drug candidates, including potential protease inhibitors, receptor antagonists, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides that incorporate the piperazine scaffold.
• Peptide Mimetics & Linker Chemistry: The allyl ester and hydroxymethyl groups provide orthogonal protection strategies, making it valuable for constructing peptide analogs and bioconjugation linkers.
• Material Science Research: Employed as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services targeting complex, multi-step organic transformations.

Basic Information

Product Name	3-Hydroxymethyl-Piperazine-1-Carboxylic Acid Allyl Ester
CAS No.	885275-39-8
Molecular Formula	C10H16N2O3
Molecular Weight	212.25 g/mol
Synonyms	1-Allyl 3-(Hydroxymethyl)piperazine-1-carboxylate; Allyl 3-(Hydroxymethyl)piperazine-1-carboxylate; 1-Carboxy-3-hydroxymethylpiperazine Allyl Ester; 3-(Hydroxymethyl)-1-piperazinecarboxylic Acid Allyl Ester; Piperazine-1-carboxylic acid, 3-(hydroxymethyl)-, allyl ester; 1-Allyloxycarbonyl-3-hydroxymethylpiperazine; 3-Hydroxymethyl-1-allyloxycarbonylpiperazine
EINECS	Contact for details

Quality Control

Our 3-Hydroxymethyl-Piperazine-1-Carboxylic Acid Allyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.