Description

3-Benzyl-1-Phenyl-Piperazine Dihydrochloride is a high-purity, pharmaceutically relevant piperazine derivative supplied as a dihydrochloride salt. This compound is a critical intermediate in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and receptor-targeted drug discovery. It is essential for medicinal chemists and pharmaceutical manufacturers engaged in the synthesis of complex molecules for preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel receptor ligands.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Research: Employed in vitro studies to investigate interactions with specific biological targets and pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Benzyl-1-Phenyl-Piperazine Dihydrochloride
CAS No.	885275-37-6
Molecular Formula	C17H20N2·2HCl
Molecular Weight	333.27 g/mol
Synonyms	1-Phenyl-3-benzylpiperazine dihydrochloride; 3-Benzyl-1-phenylpiperazine dihydrochloride; 3-Benzyl-1-phenyl-piperazine hydrochloride (1:2); 1-Phenyl-3-(phenylmethyl)piperazine dihydrochloride; BPP Dihydrochloride; 3-Benzyl-1-phenylpiperazine HCl; N-Benzyl-N'-phenylpiperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-Benzyl-1-Phenyl-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; precautions should be taken to minimize exposure to air and humidity during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.