Description

(6-tert-Butoxymethoxycarbonylmethyl-Piperazin-2-Yl)-Acetic Acid Trityl Ester is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic syntheses. It is primarily utilized in the pharmaceutical and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs) and specialized intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly those containing piperazine and protected carboxylic acid functionalities.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics for drug discovery programs targeting various diseases.
• Chemical Biology Probes: Serves as a precursor for creating labeled or tagged molecules used to study biological pathways and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of high-value, proprietary compounds.
• Academic Research: A valuable reagent for university and institutional laboratories exploring new synthetic methodologies and novel heterocyclic chemistry.
• Protecting Group Strategy: The trityl (triphenylmethyl) ester group provides orthogonal protection for carboxylic acids in complex, multi-functional molecule synthesis.

Basic Information

Product Name	(6-tert-Butoxymethoxycarbonylmethyl-Piperazin-2-Yl)-Acetic Acid Trityl Ester
CAS No.	885275-35-4
Molecular Formula	C34H40N2O6
Molecular Weight	572.70 g/mol
Synonyms	(6-((tert-Butoxycarbonyl)methoxy)methyl)-2-(carboxymethyl)piperazin-1-yl)acetic acid trityl ester; 2-[(6-{[(tert-Butoxy)carbonyl]methoxy}methyl)piperazin-2-yl]acetic acid triphenylmethyl ester; Trityl 2-(6-((tert-butoxycarbonyl)methoxy)methyl)piperazin-2-yl)acetate; Boc-protected Piperazine Acetic Acid Trityl Ester derivative; CAS 885275-35-4; Boc-Pip(OMe)-OtBu-Trityl Ester (abbreviated form)
EINECS	Contact for details

Quality Control

Every batch of (6-tert-Butoxymethoxycarbonylmethyl-Piperazin-2-Yl)-Acetic Acid Trityl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.