Description

1-(2-Bromo-Phenyl)-Piperazin-2-One is a high-purity brominated piperazinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in enabling the construction of complex nitrogen-containing heterocycles, which are essential scaffolds in modern pharmaceutical discovery and development. This compound is specifically targeted for use by research institutions and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other specialized organic materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chemical Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides.
• Material Science: Potential intermediate for creating specialized polymers or ligands with unique electronic or binding properties.
• Academic Research: Employed in university and institutional labs for methodological studies in heterocyclic chemistry and cross-coupling reactions.

Basic Information

Product Name	1-(2-Bromo-Phenyl)-Piperazin-2-One
CAS No.	885275-22-9
Molecular Formula	C10H11BrN2O
Molecular Weight	255.11 g/mol
Synonyms	1-(2-Bromophenyl)piperazin-2-one; 2-Bromophenylpiperazinone; 2-(2-Bromophenyl)-1,4-diazepan-5-one; 1-(2-Bromophenyl)-1,4-diazepan-5-one; 1-(o-Bromophenyl)piperazin-2-one; 885275-22-9; 1-(2-Bromo-phenyl)-piperazin-2-one
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.