Description

n-Cbz-4-Chloro-Piperidine is a protected piperidine derivative, a crucial chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for creating compound libraries.
• Process Chemistry: Serves as a versatile building block in the scalable synthesis of complex, nitrogen-containing heterocycles for API manufacturing.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and pesticides.
• Chemical Biology: Useful as a probe or precursor in the development of biochemical tools and labeled compounds.

Basic Information

Product Name	n-Cbz-4-Chloro-Piperidine
CAS No.	885274-98-6
Molecular Formula	C13H16ClNO2
Molecular Weight	253.72 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-chloropiperidine; 4-Chloro-1-[(phenylmethoxy)carbonyl]piperidine; 4-Chloro-N-Cbz-piperidine; 4-Chloro-1-(benzyloxycarbonyl)piperidine; Benzyl 4-chloropiperidine-1-carboxylate; 1-Cbz-4-chloropiperidine; N-Carbobenzoxy-4-chloropiperidine; 4-Chloro-1-(Cbz)piperidine
EINECS	Contact for details

Quality Control

Our n-Cbz-4-Chloro-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.