Description

3-(4-Amino-Piperidin-1-Yl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected amine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for research and development chemists who require reliable, high-quality intermediates to construct complex molecular architectures efficiently. It is primarily utilized in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and in agrochemical research for developing new crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• API Synthesis: Used as a versatile building block for constructing the core scaffolds of potential Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its piperidine-pyrrolidine motif.
• Chemical Biology & Proteomics: Employed in the synthesis of specialized probes, linkers, and reagents for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Used in university and institutional laboratories for methodological development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	3-(4-Amino-Piperidin-1-Yl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	885274-87-3
Molecular Formula	C14H27N3O2
Molecular Weight	269.39 g/mol
Synonyms	1-Boc-3-(4-amino-1-piperidinyl)pyrrolidine; tert-Butyl 3-(4-aminopiperidin-1-yl)pyrrolidine-1-carboxylate; 3-(4-Amino-1-piperidinyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 1-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)piperidin-4-amine; 885274-87-3; 3-(4-Aminopiperidin-1-yl)pyrrolidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Amino-Piperidin-1-Yl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development use under current Good Manufacturing Practice (cGMP) guidelines where applicable. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.