Description

2-(4-Boc-Piperazinyl)-2-(3,5-Dimethoxy-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a dimethoxyphenyl acetic acid backbone. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: The Boc-protected piperazine structure makes it valuable for constructing molecules targeting various protease enzymes.
• CNS Drug Development: Employed in the research and synthesis of potential therapeutics for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(3,5-Dimethoxy-Phenyl)Acetic Acid
CAS No.	885274-69-1
Molecular Formula	C19H28N2O6
Molecular Weight	380.44 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(3,5-dimethoxyphenyl)acetic acid; 2-(3,5-Dimethoxyphenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; 2-(4-Boc-piperazinyl)-2-(3,5-dimethoxy-phenyl)acetic acid; (3,5-Dimethoxyphenyl)[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]acetic acid; Boc-Pip-Dmpa-OH; tert-Butyl 4-[2-(3,5-dimethoxyphenyl)-2-hydroxyacetyl]piperazine-1-carboxylate derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(3,5-Dimethoxy-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete analytical data are provided for every shipment. We support development and commercial projects with material suitable for use under ICH guidelines and can supply material manufactured under cGMP conditions for advanced clinical stage applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.