Description

2-(4-Boc-Piperazinyl)-2-(3,4-Dimethoxy-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a dimethoxyphenyl acetic acid backbone. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and academic laboratories engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly those targeting G-protein coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Protease Inhibitor Synthesis: Serves as a key component in the development of protease inhibitors due to its specific stereochemistry and functional groups.
• Building Block for CNS Drugs: Employed in the research and development of potential therapeutics for neurological and psychiatric disorders.
• Custom Synthesis: Provided to clients for use in proprietary synthetic routes for bespoke chemical entities.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(3,4-Dimethoxy-Phenyl)Acetic Acid
CAS No.	885274-66-8
Molecular Formula	C19H28N2O6
Molecular Weight	380.44 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(3,4-dimethoxyphenyl)acetic acid; 2-(3,4-Dimethoxyphenyl)-2-[4-[(2-methyl-2-propanyl)oxycarbonyl]-1-piperazinyl]acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(3,4-dimethoxyphenyl)acetic acid; BOC-Pip-DMPA; tert-Butyl 4-[2-(3,4-dimethoxyphenyl)-2-(hydroxy)acetyl]piperazine-1-carboxylate (related form); (3,4-Dimethoxyphenyl)(4-(tert-butoxycarbonyl)piperazin-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(3,4-Dimethoxy-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.