Description

2-(4-Boc-Piperazinyl)-2-(2,4-Dichloro-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a dichlorophenyl acetic acid backbone. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of protease inhibitor libraries.
• Custom Synthesis Building Block: Employed in contract research and manufacturing (CRAM) for the custom synthesis of complex, high-value molecules.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Detail
Product Name	2-(4-Boc-Piperazinyl)-2-(2,4-Dichloro-Phenyl)Acetic Acid
CAS No.	885274-57-7
Molecular Formula	C17H22Cl2N2O4
Molecular Weight	389.27 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(2,4-dichlorophenyl)acetic acid; 2-(2,4-Dichlorophenyl)-2-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(2,4-dichlorophenyl)acetic acid; BOC-DCPAA; tert-Butyl 4-[2-(2,4-dichlorophenyl)-2-(carboxymethyl)amino]ethyl]piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(2,4-Dichloro-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We adhere to cGMP guidelines for the production of pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.