Description

2-(4-Boc-Piperazinyl)-2-(2-Pyridinyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a pyridinyl acetic acid backbone. This compound is critical for medicinal chemists in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex, nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design of peptide-like molecules with improved metabolic stability.
• Ligand Development: Employed in the creation of specialized ligands for biochemical assays and diagnostic applications.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client pipelines.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(2-Pyridinyl)Acetic Acid
CAS No.	885274-48-6
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	2-(4-Boc-Piperazinyl)-2-(2-Pyridinyl)Acetic Acid; 2-(4-[(tert-Butoxy)carbonyl]piperazin-1-yl)-2-(pyridin-2-yl)acetic Acid; 2-(2-Pyridyl)-2-[4-(tert-butoxycarbonyl)piperazino]acetic Acid; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(pyridin-2-yl)acetic Acid; 2-(N-Boc-piperazin-1-yl)-2-(pyridin-2-yl)acetic Acid; 885274-48-6; Boc-Pip-PyAA; tert-Butyl 4-(2-carboxy-2-(pyridin-2-yl)ethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(2-Pyridinyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.