Description

2-(4-Boc-Piperazinyl)-2-(4-Cyano-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a protected piperazine moiety and a versatile cyano-phenyl acetic acid backbone for further functionalization. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Peptidomimetic Synthesis: Serves as a crucial component for constructing peptide-like molecules with enhanced stability and bioavailability.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for the custom production of specialized APIs and reference standards.
• Chemical Biology Probes: Useful in the development of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(4-Cyano-Phenyl)Acetic Acid
CAS No.	885274-36-2
Molecular Formula	C18H23N3O4
Molecular Weight	345.40 g/mol
Synonyms	2-(4-((tert-Butoxycarbonyl)piperazin-1-yl))-2-(4-cyanophenyl)acetic acid; 2-(4-Cyano-phenyl)-2-[4-(tert-butoxycarbonyl)-piperazin-1-yl]-acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(4-cyanophenyl)acetic acid; 2-(4-(Boc)piperazinyl)-2-(4-cyanophenyl)acetic acid; 885274-36-2; Boc-Pip-CN-Ph-Gly-OH; tert-Butyl 4-(2-(4-cyanophenyl)-2-hydroxyacetyl)piperazine-1-carboxylate derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(4-Cyano-Phenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.