Description

2-(4-Boc-Piperazinyl)-2-(3-Cyano-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine ring and a cyano-substituted phenylacetic acid core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors and other enzyme-targeting therapeutics.
• Peptidomimetic Chemistry: The Boc-protected piperazine and phenylacetic acid structure makes it valuable for creating peptidomimetic compounds.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring high-purity, complex intermediates.
• Chemical Library Development: Used to generate diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(3-Cyano-Phenyl)Acetic Acid
CAS No.	885274-33-9
Molecular Formula	C18H23N3O4
Molecular Weight	345.40 g/mol
Synonyms	2-[4-(tert-Butoxycarbonyl)piperazin-1-yl]-2-(3-cyanophenyl)acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(3-cyanophenyl)acetic acid; 2-(3-Cyanophenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; 2-(4-Boc-1-piperazinyl)-2-(3-cyanophenyl)acetic acid; BOC-Pip-3-CN-Ph-Gly-OH; (3-Cyanophenyl)[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(3-Cyano-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.