Description

2-(4-Boc-Piperazinyl)-2-(4-Methylphenyl)Acetic Acid is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Peptide Mimetics: Used to incorporate the piperazine moiety into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and receptor binding studies.
• Chemical Biology Probes: Serves as a building block for developing molecular probes to study biological systems and enzyme functions.
• Custom Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(4-Methylphenyl)Acetic Acid
CAS No.	885274-11-3
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(p-tolyl)acetic acid; 2-(4-Boc-1-piperazinyl)-2-(4-methylphenyl)acetic acid; 2-(4-Methylphenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; Boc-Pip-MePhe-OH; N-Boc-4-(4-Methylphenyl-2-carboxy)piperazine; (4-Methylphenyl)[4-(tert-butoxycarbonyl)piperazin-1-yl]acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(4-Methylphenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.