Description

2-(4-Boc-Piperazinyl)-2-(3-Methyl-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a chiral acetic acid backbone. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, especially within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, particularly those targeting specific receptors.
• Protease Inhibitor Research: Used in the development of protease inhibitors for antiviral and anticancer applications.
• Kinase Inhibitor Synthesis: Serves as a crucial precursor in the creation of small molecule kinase inhibitors for targeted cancer therapies.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptidomimetics to enhance drug stability and bioavailability.
• Chemical Biology & Proteomics: Utilized as a tool compound or a linker in chemical probe development for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects under cGMP conditions.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(3-Methyl-Phenyl)Acetic Acid
CAS No.	885274-08-8
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(3-methylphenyl)acetic acid; 2-(4-Boc-1-piperazinyl)-2-(3-methylphenyl)acetic acid; 2-(3-Methylphenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; 2-(4-Boc-piperazin-1-yl)-2-m-tolylacetic acid; Boc-Pip-m-Tol-Gly-OH; (3-Methylphenyl)[4-[(2-methyl-2-propanyl)oxycarbonyl]-1-piperazinyl]acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(3-Methyl-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.