Description

2-(4-Boc-Piperazinyl)-2-(2-Bromo-Phenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine ring and a brominated phenylacetic acid backbone. This compound is critically important for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry and drug discovery programs. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Synthesis: Used in the production of active pharmaceutical ingredients that incorporate a functionalized piperazine moiety.
• Custom Synthesis & Scale-Up: Employed by CDMOs for process development, from milligram-scale research to kilogram-scale cGMP manufacturing.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(2-Bromo-Phenyl)Acetic Acid
CAS No.	885273-04-1
Molecular Formula	C₁₇H₂₃BrN₂O₄
Molecular Weight	399.28 g/mol
Synonyms	2-(4-Boc-Piperazinyl)-2-(2-Bromophenyl)Acetic Acid; 2-(2-Bromophenyl)-2-[4-[(tert-butoxy)carbonyl]piperazin-1-yl]acetic Acid; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(2-bromophenyl)acetic Acid; 2-Bromo-α-(4-(tert-butoxycarbonyl)piperazinyl)benzeneacetic Acid; N-Boc-4-(2-Bromo-α-carboxyphenyl)piperazine; 885273-04-1; tert-Butyl 4-(2-(2-bromophenyl)-2-carboxyethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(2-Bromo-Phenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.