Description

4-[Carboxy-(2-Chloro-Phenyl)-Methyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is essential for research and development chemists requiring a reliable, high-quality building block for complex molecule construction. It is primarily utilized in the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new therapeutic candidates.
• Process Chemistry: Employed in scale-up and route development for the commercial manufacturing of pharmaceuticals.
• Custom Synthesis: Serves as a starting material for the preparation of specialized piperazine and phenyl-containing derivatives.
• Bioconjugation & Labeling: Potential use in creating labeled compounds for diagnostic or research purposes due to its reactive functional groups.

Basic Information

Product Name	4-[Carboxy-(2-Chloro-Phenyl)-Methyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride
CAS No.	885272-96-8
Molecular Formula	C18H25ClN2O4 • HCl
Molecular Weight	405.32 g/mol (Free base: 368.86 g/mol)
Synonyms	tert-Butyl 4-[(2-chlorophenyl)(carboxy)methyl]piperazine-1-carboxylate hydrochloride; 1-Boc-4-[(2-chlorophenyl)(carboxy)methyl]piperazine hydrochloride; 4-[(2-Chlorophenyl)(hydroxymethyl)carbonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester hydrochloride; 1-(tert-Butoxycarbonyl)-4-[(2-chlorophenyl)(carboxy)methyl]piperazine hydrochloride; (2-Chlorophenyl)[(4-(tert-butoxycarbonyl)piperazin-1-yl)]acetic acid hydrochloride; BOC-Pip-(2-Cl-Ph)-Gly-OH • HCl
EINECS	Contact for details

Quality Control

Our 4-[Carboxy-(2-Chloro-Phenyl)-Methyl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.