Description

1-Isopropyl-(S)-2-Methylpiperazine Dihydrochloride is a high-purity, chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate stereochemically defined piperazine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Agrochemical Research: Used in the synthesis of advanced, stereospecific pesticides and herbicides.
• Chemical Biology: Serves as a scaffold for constructing molecular probes and tool compounds for biological target investigation.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & Process Chemistry: A valuable reagent for methodological development and scale-up studies in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Isopropyl-(S)-2-Methylpiperazine Dihydrochloride
CAS No.	884199-34-2
Molecular Formula	C8H19Cl2N2
Molecular Weight	209.16 g/mol
Synonyms	(S)-1-Isopropyl-2-methylpiperazine dihydrochloride; (S)-2-Methyl-1-(propan-2-yl)piperazine dihydrochloride; (2S)-1-(Propan-2-yl)-2-methylpiperazine dihydrochloride; 1-(1-Methylethyl)-(2S)-2-methylpiperazine dihydrochloride; (S)-1-Isopropyl-2-methylpiperazine hydrochloride (1:2); Piperazine, 1-(1-methylethyl)-2-methyl-, (2S)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-(S)-2-Methylpiperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.